Erich Gulbins Selected Research

Sphingomyelin Phosphodiesterase (Sphingomyelinase)

1/2022	Lung Transplantation for Adult Respiratory Distress Syndrome after SARS-CoV-2 Infection.
1/2022	Association between FIASMA psychotropic medications and reduced risk of intubation or death in individuals with psychiatric disorders hospitalized for severe COVID-19: an observational multicenter study.
1/2022	The acid sphingomyelinase/ceramide system in COVID-19.
12/2021	Neutral sphingomyelinase mediates the co-morbidity trias of alcohol abuse, major depression and bone defects.
12/2021	Acid sphingomyelinase promotes SGK1-dependent vascular calcification.
12/2021	Repurposing antidepressants inhibiting the sphingomyelinase acid/ceramide system against COVID-19: current evidence and potential mechanisms.
1/2021	Ex vivo assay to evaluate the efficacy of drugs targeting sphingolipids in preventing SARS-CoV-2 infection of nasal epithelial cells.
1/2021	The Role of Acid Sphingomyelinase Inhibition in Repetitive Mild Traumatic Brain Injury.
1/2021	Inhibition of acid sphingomyelinase by ambroxol prevents SARS-CoV-2 entry into epithelial cells.
11/2020	Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells.

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Erich Gulbins Research Topics

Disease

68	Infections 01/2022 - 10/2003
39	Cystic Fibrosis (Mucoviscidosis) 01/2022 - 01/2008
32	Neoplasms (Cancer) 05/2022 - 10/2003
22	Inflammation (Inflammations) 01/2022 - 04/2008
15	Pneumonia (Pneumonitis) 11/2021 - 04/2008
15	Bacterial Infections (Bacterial Infection) 01/2021 - 01/2008
13	Sepsis (Septicemia) 01/2019 - 07/2006
10	Pseudomonas Infections 01/2021 - 04/2008
8	COVID-19 01/2022 - 11/2020
7	Alcoholism (Alcohol Abuse) 12/2021 - 01/2010
7	Virus Diseases (Viral Diseases) 01/2021 - 12/2002
6	Major Depressive Disorder (Major Depressive Disorders) 01/2022 - 11/2009
6	Burns 01/2021 - 11/2016
6	Hepatolenticular Degeneration (Wilson's Disease) 05/2015 - 02/2007
6	Anemia 01/2015 - 01/2006
5	Lung Diseases (Lung Disease) 01/2022 - 12/2008
5	Melanoma (Melanoma, Malignant) 10/2020 - 07/2012
5	Glioma (Gliomas) 01/2017 - 09/2007
5	Malaria 05/2015 - 01/2008
4	Mood Disorders (Mood Disorder) 01/2022 - 01/2008
4	Niemann-Pick Diseases (Niemann Pick Disease) 12/2021 - 01/2014
4	Sickle Cell Anemia (Hemoglobin S Disease) 03/2020 - 01/2009
4	Multiple Sclerosis 01/2019 - 11/2002
4	Acute Lung Injury 01/2018 - 02/2004
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 01/2020
3	Vesicular Stomatitis 01/2021 - 11/2020
3	Neoplasm Metastasis (Metastasis) 01/2017 - 06/2015
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2016 - 10/2003
3	Reperfusion Injury 01/2016 - 10/2003
3	beta-Thalassemia (Cooley's Anemia) 05/2015 - 01/2009
3	Iron Deficiencies 05/2015 - 01/2009
3	Alzheimer Disease (Alzheimer's Disease) 01/2014 - 01/2007
3	Shock 01/2011 - 01/2007
2	Leukemia 02/2022 - 07/2015
2	Nervous System Diseases (Neurological Disorders) 01/2022 - 06/2007
2	Ventilator-Associated Pneumonia 11/2021 - 01/2019
2	Wounds and Injuries (Trauma) 01/2021 - 06/2015
2	Mental Disorders (Mental Disorder) 01/2021 - 01/2017
2	Critical Illness (Critically Ill) 10/2020 - 03/2020
2	Asthma (Bronchial Asthma) 01/2020 - 12/2008
2	Farber Lipogranulomatosis 12/2019 - 01/2018
2	Endotoxemia 12/2019 - 01/2019
2	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2019 - 11/2002
2	Chronic Obstructive Pulmonary Disease (COPD) 01/2019 - 01/2018
2	Emphysema 01/2019 - 12/2008
2	Staphylococcal Infections 04/2018 - 01/2016
2	Edema (Dropsy) 01/2018 - 06/2015

Drug/Important Bio-Agent (IBA)

90	CeramidesIBA 01/2022 - 10/2003
68	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 01/2022 - 12/2002
63	AcidsIBA 01/2022 - 12/2002
29	SphingolipidsIBA 01/2022 - 12/2006
24	Amitriptyline (Elavil)FDA LinkGeneric 01/2021 - 01/2008
21	SphingosineIBA 01/2021 - 09/2014
15	LipidsIBA 01/2022 - 03/2010
14	EnzymesIBA 01/2021 - 07/2005
14	CytokinesIBA 01/2020 - 06/2004
13	Antidepressive Agents (Antidepressants)IBA 01/2022 - 11/2009
10	Proteins (Proteins, Gene)FDA Link 01/2021 - 12/2006
9	Anti-Bacterial Agents (Antibiotics)IBA 11/2021 - 01/2015
9	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 12/2019 - 04/2008
8	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2020 - 09/2007
7	Acid CeramidaseIBA 01/2021 - 01/2009
5	Potassium Channels (Potassium Channel)IBA 05/2022 - 07/2015
5	Phosphates (Orthophosphate)IBA 12/2021 - 01/2008
5	InflammasomesIBA 12/2019 - 01/2014
5	Death Domain ReceptorsIBA 08/2011 - 01/2006
4	Gemcitabine FDA Link 05/2022 - 09/2007
4	Pharmaceutical PreparationsIBA 05/2022 - 12/2009
4	Fluoxetine (Prozac)FDA LinkGeneric 01/2022 - 06/2010
4	SphingomyelinsIBA 01/2017 - 01/2010
4	PhosphatidylserinesIBA 01/2014 - 02/2007
3	Kv1.3 Potassium ChannelIBA 04/2022 - 07/2015
3	Phenobarbital (Luminal)FDA Link 01/2021 - 09/2014
3	SARS-CoV-2 spike proteinIBA 01/2021 - 11/2020
3	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 10/2020 - 12/2002
3	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2019 - 01/2016
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019 - 07/2005
3	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 04/2008
3	Ion Channels (Ion Channel)IBA 10/2017 - 09/2013
3	LigandsIBA 06/2017 - 02/2005
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2017 - 09/2014
3	CationsIBA 08/2010 - 01/2007
2	Neutral CeramidaseIBA 01/2022 - 12/2016
2	AntibodiesIBA 01/2022 - 06/2017
2	Expectorants (Mucolytics)IBA 11/2021 - 01/2021
2	AntioxidantsIBA 10/2021 - 01/2019
2	PlasticsIBA 01/2021 - 01/2019
2	Tricyclic Antidepressive Agents (Tricyclic Antidepressants)IBA 01/2021 - 01/2014
2	Sertraline (Zoloft)FDA LinkGeneric 11/2020 - 06/2010
2	Cathepsin DIBA 11/2020 - 11/2009
2	NADPH Oxidases (NAD(P)H oxidase)IBA 11/2020 - 09/2008
2	CalciumIBA 01/2020 - 06/2016
2	SmokeIBA 01/2019 - 06/2014
2	Biomarkers (Surrogate Marker)IBA 12/2018 - 11/2015

Therapy/Procedure

13	Therapeutics 04/2022 - 05/2010
10	Drug Therapy (Chemotherapy) 01/2021 - 10/2003
5	Ligation 01/2019 - 01/2008
3	Artificial Respiration (Mechanical Ventilation) 11/2021 - 11/2017
2	Extracorporeal Membrane Oxygenation 01/2022 - 03/2020
2	Punctures 01/2019 - 01/2019